abstract：:Skin biopsy specimens from 24 patients with different lichenoid skin diseases that had been proved histologically were studied immunohistologically. Marked differences were noted in the number of OKT6+/S100+ Langerhans cells within the epidermis and dermis in the lesional skin between lichen planus (and its related di...

journal_title：Journal of the American Academy of Dermatology

authors： Shiohara T,Moriya N,Tanaka Y,Arai Y,Hayakawa J,Chiba M,Nagashima M

更新日期：1988-01-01 00:00:00

abstract：:During 1 year of continuous suppressive therapy for frequent recurrent genital herpes, about 44% of patients taking 400 mg acyclovir twice a day had no recurrences and 4% of patients taking placebo had no recurrences (i.e., fewer patients taking acyclovir had recurrences, and when they did there were fewer recurrences...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA

更新日期：1988-01-01 00:00:00

abstract：:This study was designed to investigate the relationship between alteration of skin surface pH and the development of skin irritation. Application of a phosphate/borate/acetate buffer adjusted to pH 4.0-10.5 in a standard chamber irritation test did not result in significant clinical irritation. This was true in spite ...

journal_title：Journal of the American Academy of Dermatology

authors： Murahata RI,Toton-Quinn R,Finkey MB

更新日期：1988-01-01 00:00:00

abstract：:A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

journal_title：Journal of the American Academy of Dermatology

authors： King DH

更新日期：1988-01-01 00:00:00

abstract：:We hereby report a case presenting a rare form of secondary syphilis with an unusual nodular eruption accompanied by pruritus and generalized lymphadenopathy, bearing a striking resemblance to lymphoma. The histologic picture was also misleading and was compatible with lymphocytoma cutis. The diagnosis was eventually ...

journal_title：Journal of the American Academy of Dermatology

authors： Hodak E,David M,Rothem A,Bialowance M,Sandbank M

更新日期：1987-11-01 00:00:00

abstract：:Reflections from instruments in the surgical field involving the CO2 laser beam present a serious ocular hazard. In addition to the use of plastic or glass protective eyewear, this hazard can be minimized by utilizing anodized instruments and recognizing the specific distances at which various reflections are no longe...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman NR,Saleeby ER,Rubin MG,Sandu T,Krull EA

更新日期：1987-11-01 00:00:00

abstract：:Blood eosinophilia is a common feature of eosinophilic fasciitis and is variably reported in systemic sclerosis and localized scleroderma. Since these diseases share cutaneous fibrosis as the final outcome and have other clinical and pathologic features that are difficult to differentiate, the presence of blood eosino...

journal_title：Journal of the American Academy of Dermatology

authors： Falanga V,Medsger TA Jr

更新日期：1987-10-01 00:00:00

abstract：:A recent familial case of hereditary epidermolytic palmoplantar keratoderma (Vörner type) that was treated with orally administered etretinate is reported herein. A review of the literature with regard to the clinical, genetic, and laboratory features of this rare genodermatosis is also presented. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kanitakis J,Tsoitis G,Kanitakis C

更新日期：1987-09-01 00:00:00

abstract：:Four patients with severe psoriasis have been treated with oral cyclosporine for 6 months. Two had generalized erythroderma and two had extensive plaque-type psoriasis; all had either become unresponsive to or were unable to use other accepted treatments. All four patients responded rapidly and were completely clear o...

journal_title：Journal of the American Academy of Dermatology

authors： Picascia DD,Garden JM,Freinkel RK,Roenigk HH Jr

更新日期：1987-09-01 00:00:00

abstract：:We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bon...

journal_title：Journal of the American Academy of Dermatology

authors： Welsh O,Sauceda E,Gonzalez J,Ocampo J

更新日期：1987-09-01 00:00:00

abstract：:The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...

journal_title：Journal of the American Academy of Dermatology

authors： Lowe NJ,Dromgoole SH,Sefton J,Bourget T,Weingarten D

更新日期：1987-08-01 00:00:00

abstract：:A 3-year-old boy presented two patches of light, bright, smooth, uncombable hair that were morphologically different from the rest of the hairs. Examination under scanning electron microscopy showed the morphologic characteristics of pili canaliculi and trianguli. Clinical and ultrastructural features seemed to corres...

journal_title：Journal of the American Academy of Dermatology

authors： Ravella A,Pujol RM,Noguera X,de Moragas JM

更新日期：1987-08-01 00:00:00

abstract：:We report a case of fatal pancreatitis heralded by the presence of cutaneous panniculitis without abdominal pain or other stigmata of the disease. Although cutaneous fat necrosis has been associated with pancreatitis, it is unusual as the presenting complaint of this relatively common disease. In vitro evidence sugges...

journal_title：Journal of the American Academy of Dermatology

authors： Berman B,Conteas C,Smith B,Leong S,Hornbeck L 3rd

更新日期：1987-08-01 00:00:00

abstract：:A study comparing direct immunofluorescence assay using a new monoclonal antibody specific for a varicella-zoster virus glycoprotein complex, the Tzanck smear, and virus isolation for detection of varicella-zoster virus in 56 patients with clinically apparent herpes zoster is presented. Of 47 patients with clinical he...

journal_title：Journal of the American Academy of Dermatology

authors： Sadick NS,Swenson PD,Kaufman RL,Kaplan MH

更新日期：1987-07-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：:Cutaneous leishmaniasis (oriental sore) is characterized by slowly evolving inflammatory lesion(s) that are nodular, noduloulcerative, or ulcerative and that heal spontaneously with scar(s) in 3 to 12 months. In the course of a comprehensive study of cutaneous leishmaniasis due to Leishmania major in an endemic focus ...

journal_title：Journal of the American Academy of Dermatology

authors： Kubba R,Al-Gindan Y,el-Hassan AM,Omer AH

更新日期：1987-06-01 00:00:00

abstract：:The PA Patch, a new multiple-antigen, predispensed patch testing device, was compared to the Finn Chamber in subjects with previous positive patch tests. After pressing the PA Patch well, the PA Patch performed as well as the Finn Chamber in nine subjects tested. ...

journal_title：Journal of the American Academy of Dermatology

authors： Marks JG Jr,Westheim A,Snipes W

更新日期：1987-05-01 00:00:00

abstract：:A 65-year-old man with insulin-dependent diabetes developed intractable pruritus preceding weight loss and increasing fatiguability. Esophagogastroduodenoscopy revealed infection with Candida, cytomegalovirus, and Cryptosporidium. His T cell helper/suppressor ratio was inverted, and the serum human immunodeficiency vi...

journal_title：Journal of the American Academy of Dermatology

authors： Shapiro RS,Samorodin C,Hood AF

更新日期：1987-05-01 00:00:00

abstract：:A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

journal_title：Journal of the American Academy of Dermatology

authors： Jaworsky C,Ratz JL,Dijkstra JW

更新日期：1987-04-01 00:00:00

abstract：:A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

journal_title：Journal of the American Academy of Dermatology

authors： De Villez RL

更新日期：1987-03-01 00:00:00

abstract：:This study was conducted to further evaluate the safety and efficacy of 3% topical minoxidil in the treatment of extensive alopecia areata. Patients were assigned to one of two treatment regimens in a double-blind manner. One group applied 3% minoxidil to the scalp twice daily for 64 weeks; the other group applied pla...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH

更新日期：1987-03-01 00:00:00

abstract：:In vivo, topical minoxidil therapy is associated with changes in the follicular epithelium, tissue and blood lymphocyte populations, lymphocyte blastogenic response to mitogens, and perifollicular vasculature. Biopsy specimens taken from areas of terminal hair regrowth show a dose-dependent increase in hair follicle l...

journal_title：Journal of the American Academy of Dermatology

authors： Fiedler-Weiss VC

更新日期：1987-03-01 00:00:00

abstract：:Sixty patients were treated for tinea pedis with 2% topical ketoconazole cream either once or twice daily. All diagnoses were confirmed mycologically. They were randomly assigned in a double-blind study into three groups on the basis of their clinical lesions, that is, vesicular pedis, interdigital pedis, and hyperker...

journal_title：Journal of the American Academy of Dermatology

authors： Greer DL

更新日期：1987-03-01 00:00:00

abstract：:An examination of 380 patients was accomplished in order to determine the frequency of occurrence of pigmentary demarcation lines in an unselected population. Both white and black patients were included in the study, and there was an equal sex distribution. Separation of data by age groups enabled us to determine that...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Carter JM,Rodman OG

更新日期：1987-03-01 00:00:00

abstract：:A 60-year-old man with postpolycythemic myeloid metaplasia developed acute neutrophilic dermatosis (Sweet's syndrome), which responded to systemic steroid therapy. Six months later he developed acute myelogenous blast crisis refractory to leukemic induction therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Horan MP,Redmond J,Gehle D,Dabe IB,Fort SL

更新日期：1987-02-01 00:00:00

abstract：:Platelike osteoma cutis is a rare lesion that is most often congenital. An 85-year-old man developed a plate, or sheet, of subcutaneous bone in an area previously affected by morphea. The sheet of bone was visualized with a variety of imaging technics, including xerography, computed tomography, and radionuclide bone s...

journal_title：Journal of the American Academy of Dermatology

authors： Monroe AB,Burgdorf WH,Sheward S

更新日期：1987-02-01 00:00:00

abstract：:Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Venencie PY,Bradley RR,Winkelmann RK

更新日期：1987-02-01 00:00:00

abstract：:A newborn infant with subcutaneous fat necrosis and hypercalcemia is presented. Literature on the association between subcutaneous fat necrosis of the newborn and hypercalcemia is reviewed. Affected infants generally experience severe perinatal difficulties. Both vaginal deliveries and cesarean sections can be associa...

journal_title：Journal of the American Academy of Dermatology

authors： Norwood-Galloway A,Lebwohl M,Phelps RG,Raucher H

更新日期：1987-02-01 00:00:00

abstract：:We report the coexistence of pemphigus vulgaris and Paget's disease of the nipple in a patient with a documented history of pemphigus and a 2-year complaint of an eczematous breast lesion. A biopsy taken from the lesion showed the characteristic histologic features of both pemphigus and Paget's disease of the nipple. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rae V,Gould E,Ibe MJ,Penneys NS

更新日期：1987-01-01 00:00:00

abstract：:A case of Flegel's disease, or hyperkeratosis lenticularis perstans, is reported. This rare chronic disorder is characterized by asymptomatic hyperkeratotic papules, usually located on the lower extremities. Most reported cases have been from Europe. We report a case of hyperkeratosis lenticularis perstans from our in...

journal_title：Journal of the American Academy of Dermatology

authors： Pearson LH,Smith JG Jr,Chalker DK

更新日期：1987-01-01 00:00:00

abstract：:A patient with acquired immunodeficiency syndrome presented with multiple pruritic papules and nodules over the trunk and extremities. Biopsy specimens from two of these lesions contained granules within abscesses of the papillary dermis. There were numerous gram-positive cocci within the granules. Culture of one lesi...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Kitces EN,Neafie RC

更新日期：1987-01-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：:Various cutaneous signs and syndromes have been associated with hepatitis B virus infection. This is a report of the clinical, pathologic, immunofluorescence, and immunoperoxidase studies of peculiar papular lesions that have been observed to occur during the chronic phase of hepatitis B virus infection. A total of th...

journal_title：Journal of the American Academy of Dermatology

authors： Martínez MI,Sánchez JL,López-Malpica F

更新日期：1987-01-01 00:00:00

abstract：:The acute complications that may result in failure of the surgical procedure are discussed. These include bleeding, hematoma, infection, dehiscence, and necrosis. The background of each is covered in detail and an attempt is made to show the interrelationships among them. The purpose of this communication is to aid in...

journal_title：Journal of the American Academy of Dermatology

authors： Salasche SJ

更新日期：1986-12-01 00:00:00

abstract：:We report on a patient with a syndrome characterized by smooth facial papules and nodules; alopecia of the eyebrows, eyelashes, and most body hair; mild alopecia of scalp hair; possibly hypohidrosis; and myasthenia gravis. The clinical, histologic, and immunohistochemical findings are compared with classic and desmopl...

journal_title：Journal of the American Academy of Dermatology

authors： Starink TM,Lane EB,Meijer CJ

更新日期：1986-11-01 00:00:00

abstract：:A 49-year-old man presented with an acute onset of folliculitis on his right cheek. The folliculitis was unresponsive to antibiotics. A potassium hydroxide preparation of a scraping from the affected area revealed the presence of numerous Demodex mites. The patient was treated with topical crotamiton (Eurax) cream res...

journal_title：Journal of the American Academy of Dermatology

authors： Purcell SM,Hayes TJ,Dixon SL

更新日期：1986-11-01 00:00:00

abstract：:Using metaphase chromosome spreads as substrate for indirect immunofluorescence technic, we observed anticentromere antibody in three of twenty-five patients affected with various clinical forms of localized scleroderma. Anticentromere antibody is generally considered a serologic marker of the CREST syndrome, a more b...

journal_title：Journal of the American Academy of Dermatology

authors： Ruffatti A,Peserico A,Glorioso S,Fiocco U,Rossi L,Gambari P,Todesco S

更新日期：1986-10-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:A persistent periocular dermatitis resulting from the prolonged use of topical fluorinated corticosteroids that resembled the perioral variety was observed in three patients. All topical therapy was ineffective until systemic tetracycline was administered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher AA

更新日期：1986-10-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00